- Rafael Nadal (Spain) defeated Daniill Medvedev (Russia) 2-6,6-7,6-4,6-4,7-5 to win the Men’s Single title at Australian Open 2022.
- This is his 21st Major title, becoming the first male player to do so. In women’s tennis, Margaret Court (Australian) has 24 singles majors, an all-time record.
Complete winner list of Australian Open Tennis Title 2022:
| 2022 Event | Winners | Runner-Up |
| Men’s Singles | Rafael Nadal | Daniil Medvedev |
| Women’s Singles | Ashleigh Barty | Danielle Collins |
| Men’s Doubles | Thanasi Kokkinakis and Nick Kyrgios | Matthew Ebden and Max Purcell |
| Women’s Doubles | Barbora Krejčíková and Kateřina Siniaková | Anna Danilina and Beatriz Haddad Maia |
| Mixed Doubles | Kristina Mladenovic and Ivan Dodig | Jaimee Fourlis and Jason Kubler |